@Moondra I would recommend using a single 2080Ti and not 2xGPU to avoid the hassles of cooling. You’ll have to configure all of the complications of maybe liquid cooling both of them.
I’m not against that, but it seemed to be pretty intimidating to me, so I decided to stick to a single GPU.
Also-I’m not sure of the current scenario but Intel offers some speedup because of the MKL scernios so it might be a better pick than AMD (please verify)
For the Mobo-make sure each GPU gets plenty PCIE lines. Note: M.2 drives use PCIE lines, also you would want to make sure that you’ll have enough RAM for your future needs (64 or 128GB)