Advantages in oflloading 2d/3d to AMD gpu

In you experice there is any advantage in avoiding loading the compute card in managing also the GUI.
Ordered my new PC components will arrive in next week or so.
I will reuse the ssd/hdd from my old PC, but can also reuse the AMD GPU.
Will have Win10 on Ssd1 and Ubuntu on Ssd2.
Appear there are some troubles mixing AMD and Nvidia gpu on the same setup, so was wondering if there is a real advantage in avoiding the Nvidia card used for compute any graphics related work or I can avoid the troubles of this mixing.