I am a Professor of Biomedical Informatics at the University of Texas Health Science Center at Houston. I received a PhD in Artificial Intelligence in 1991 from The Ohio State University. My PhD work was on expert systems for medical diagnosis, using Allen Newell’s SOAR architecture. When the expert system funding started to drop off in the 90’s I shifted to cognitive support and cognitive modeling, largely using John Anderson’s ACT-R architecture. Two of my first grants, from the Office of Naval Research, were on hybrid (symbolic-connectionist) models of decision making. In 1998 I moved to Houston, TX to help start a new school of biomedical informatics. I was at the University of Kentucky from 2010 to 2013 to begin a new informatics program and lead the informatics component of UK’s Clinical Translational Science Award. I returned to UT Houston in 2013 where I now spend much of my time working with our clinical partners on healthcare analytics for clinical quality improvement and on secondary use of clinical care data for translational science.